van Erp NP, Baker SD, Zandvliet AS, Ploeger BA, den Hollander M, Chen Z, den Hartigh J, König-Quartel JM, Guchelaar HJ, Gelderblom H. Marginal increase of sunitinib exposure by grapefruit juice. (2), Vitamin C, a key nutrient in grapefruit, isn’t typically toxic in large amounts. You’ll want to avoid applying pure essential oils to your face though — make sure you dilute a few drops in a carrier oil first. J Clin Pharmacol. View abstract. Dramatic inhibition of amiodarone metabolism induced by grapefruit juice. View abstract. J Clin Pharmacol. Zhang YD, Lorenzo B, Reidenberg MM. Since vitamin C is water soluble, any excess amount that your body doesn’t need is removed via urine, which may be possible after eating one grapefruit. Clin Pharmacol Ther 2003;74:121-29 . Clin Pharmacol Ther 2000;67:690. Grapefruit is high in vitamin C, soluble fiber, and antioxidants which makes it a good addition to any diet. Therefore, you should be sure about the dosage of the grapefruit ingredient that you are taking. Nutr.J. View abstract. Dresser GK, Bailey DG, Leake BF, et al. Dresser GK, Spence JD, Bailey DG. Holmberg MT, Tornio A, Joutsi-Korhonen L, Neuvonen M, Neuvonen PJ, Lassila R, Niemi M, Backman JT. Bailey, D. G., Arnold, J. M., Bend, J. R., Tran, L. T., and Spence, J. D. Grapefruit juice-felodipine interaction: reproducibility and characterization with the extended release drug formulation. Spraying chicken skin with selected chemicals to reduce attached Salmonella typhimurium. 7. Clin Pharmacol Ther 1998;64:286-8. Bailey DG, Spence JD, Munoz C, Arnold JM. Shoaf SE, Mallikaarjun S, Bricmont P. Effect of grapefruit juice on the pharmacokinetics of tolvaptan, a non-peptide arginine vasopressin antagonist, in healthy subjects. You can add health benefits to pancakes, cookies, bread, and more simply by swapping all-purpose flour for one of these options. Effects of grapefruit juice on cortisol metabolism in healthy male Chinese subjects. Grapefruit juice-lovastatin interaction. Rogers JD, Zhao J, Liu L, et al. View abstract. Von Woedtke T, Schluter B, Pflegel P, et al. Warfarin (Coumadin) interacts with GRAPEFRUIT. Am J Clin Nutr 2006;83(5):1097-1105. Grapefruit juice is in different-different colors.There are many health benefits of grapefruit. Terfenadine (Seldane) interacts with GRAPEFRUIT. 2013 Jun;75(6):1488-96. View abstract. Product information for Cordarone. (2) But grapefruit does have a tinge of natural sweetness to it. Eur J Clin Pharmacol 2001;56:799-803. View abstract. Drinking grapefruit juice while taking losartan (Cozaar) might decrease the effectiveness of losartan. Pisarik, P. Blood pressure-lowering effect of adding grapefruit juice to nifedipine and terazosin in a patient with severe renovascular hypertension. Br J Clin Pharmacol 2005;60(5):494-497. Refrigeration can help extend the life by an additional week or two. Drinking grapefruit juice while taking estrogens might increase estrogen levels and side effects associated with estrogen such as breast cancer. (2) On the grapefruit diet, you eat large quantities of grapefruit and grapefruit juices in an effort to burn more fat. Bailey DG, Dresser GK. Chem Res Toxicol 1998;11:252-9. Some research shows that eating vitamin C-rich citrus fruits, including grapefruit and others, might improve lung function in people with asthma. View abstract. View abstract. Lilja JJ, Kivisto KT, Neuvonen PJ. Carbamazepine (Tegretol) interacts with GRAPEFRUIT. J Agric Food Chem 3-8-2006;54(5):1887-1892. Contraception 1996;53:41-7. Impact of citrus soft drinks relative to grapefruit juice on ciclosporin disposition. Effect of grapefruit juice dose on grapefruit juice-triazolam interaction: repeated consumption prolongs triazolam half-life. Xenobiotica. Phytother Res. Clin Pharmacol Ther 2002;71:11-20. Eur J Clin Pharmacol 2000;56:411-5. View abstract. View abstract. Grapefruit juice and its flavonoids inhibit 11 beta-hydroxysteroid dehydrogenase. Grapefruit might increase how much cyclosporine (Neoral, Sandimmune) the body absorbs. Lee, M., Min, D. I., Ku, Y. M., and Flanigan, M. Effect of grapefruit juice on pharmacokinetics of microemulsion cyclosporine in African American subjects compared with Caucasian subjects: does ethnic difference matter? 2000;159(12):895-7. Crit Rev Clin Lab Sci 2003;40(3):295-335. Vitamins and Supplements to Avoid with Hepatitis C. Quiz: What Do You Know About Vitamin B12 Deficiency? Dahan A, Amidon GL. Fuhr U. Suggested Read:- 7 Major Side Effects of Consuming Too Many Jujubes (10) Side Effects of Eating Too Much Fiber. View abstract. Drinking grapefruit while taking caffeine might increase the side effects of caffeine including jitteriness, headache, and a fast heartbeat. Influence of grapefruit juice on cisapride pharmacokinetics. Health Benefits and Side Effects of Grapefruit ! A: Grapefruit is an excellent source of vitamin C, but it contains just slightly less vitamin C than oranges. J Clin Pharmacol 2002;42:1165-70. Effect of grapefruit juice and naringin on nisoldipine pharmacokinetics. How to Cut Grapefruit Properly ! Interaction between grapefruit juice and diazepam in humans. View abstract. A prospective study of diet and adult-onset asthma. Taking grapefruit juice along with clomipramine (Anafranil) might increase the effects and side effects of clomipramine (Anafranil). View abstract. A., van Rooij, J., Lentjes, G. W., Arbouw, F., van Bree, J. Beverage use and risk of kidney stones in women. Ku, Y. M., Min, D. I., and Flanigan, M. Effect of grapefruit juice on the pharmacokinetics of microemulsion cyclosporine and its metabolite in healthy volunteers: does the formulation difference matter? Ther Drug Monit 2000;22:131-6. View abstract. Weight loss, here you come. As a result, grapefruit grew exponentially in popularity across the country. View abstract. View abstract.